PHYTOCHEMISTRY DIVISION

Profile

Phytochemistry division forms core activity of the centre and has played significant role for authentication of genuine raw drugs used in Ayurvedic industry. The data base of the division comprises chemical finger prints of more than 100 genuine raw drugs. The division focuses on identification and isolation of active molecules from medicinal plants.  The Division is equipped with sophisticated instruments including High Performance Liquid Chromatography, Gas Chromatography, Gas Chromatography-Mass Spectrometer, Liquid Chromatography-Mass Spectrometer, Fourier Transform Infra Red Spectroscopy, UV-Visible Spectrophotometer etc. The research outcome of the division is evidenced by good number of research articles in various national and international journals published by world renowned publishers like Elsevier, Taylor & Francis, Springer, Hindawi etc


RESEARCH PROGRAMMES:

  • Standardization of raw drugs used in Ayurvedic medicines
  • Isolation and characterization of active compounds from various medicinal plants
  • Chemical characterization of controversial raw drugs/ their source plants
  • Inter and Intra-specific chemical variability studies
  • Optimization of methods for the sustainable/judicious utilization of raw drugs
  • Chemical fidelity studies on tissue cultured Ayurvedic medicinal plants
  • Scientific validation of different detoxification process mentioned in classical Ayurvedic texts
  • To function as a central facility in Phytochemistry for students, researchers and to other bonafide users

Major Achievements:

  • Chemical fingerprints were developed for 128 species using different chromatographic techniques like TLC, HPLC and GC for the identification of genuine raw drugs.
  • 42 compounds have been isolated from different Ayurvedic medicinal plants. Quantification of species specific marker compounds was done in 38 species
  • Plant part substitution studies were carried out in five species to evaluate the possibilities of using other parts instead of root which will help sustainable utilization
  • HPLC-ESI-MS method has been developed for the rapid  identification of major phyto constituents from finished Ayurvedic formulation
  • Analytical methods were developed for the identification of superior lines with high content of  active molecules
  • DAD-ESI-MS/MS methods have been developed for the identification of polyphenols from various medicinal plants
  • Evidence based scientific validation has been done in different detoxification process mentioned in classical texts using various analytical methods.
  • Training imparted for 89 postgraduate students, 5 M. Phil and 3 Ph.D scholars.
  • 42 articles were published in various national and international journals with good impact factor

Awards

Facilities

  • High Pressure Liquid Chromatography ( HPLC-analytical and Preparative)
  • Gas Chromatography (GC)
  • UV-Visible Spectrophotometer ( UV)
  • Fourier Transform Infra Red Spectrophotometer (FTIR)
  • Gas Chromatography Mass Spectroscopy (GC/MS)
  • Q-TOF Liquid Chromatography mass Spectroscopy (LC/MS)
  • Cooling Centrifuge
  • Rotary evaporator
  • Sonicator
  • UV -TLC cabinet

Publications

 

In Journals:

  • Published: (40)

In symposium/seminar: (11)

Scientists

1. Dr. Sulaiman C. T. ( Senior Scientist)

2. Dr. Sunil A.R. (Scientist)

3. Lijini K.R. (Scientist)

  • "The Centre for Medicinal Plants Research functions as a pioneer institute in the area of research, education, conservation and popularisation of Ayurvedic medicinal plants."

  • "The Centre for Medicinal Plants Research functions as a pioneer institute in the area of research, education, conservation and popularisation of Ayurvedic medicinal plants."

  • "The Centre for Medicinal Plants Research functions as a pioneer institute in the area of research, education, conservation and popularisation of Ayurvedic medicinal plants."